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Janeway lesion
Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are indicative of infective endocarditis. Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis.〔 They are caused by septic emboli which deposit bacteria, forming microabscesses.〔Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th ed., Churchill Livingstone 2009.〕 Janeway lesions are distal, flat, ecchymotic, and painless.
Osler's nodes and Janeway lesions are similar, but Osler's nodes present with tenderness and are of immunologic origin.
==Eponym==
They are named after Edward Janeway (1841-1911), a prominent American physician and pathologist who initially described the lesions.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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